Renal sodium retention in preascitic cirrhosis: Expanding knowledge, enduring uncertainties
نویسندگان
چکیده
منابع مشابه
Sodium homeostasis with chronic sodium loading in preascitic cirrhosis.
BACKGROUND Preascitic cirrhotic patients receiving 200 mmol of sodium daily for seven days remain in positive sodium balance. Thereafter, sodium handling is unknown. AIM To assess renal sodium handling in preascitic cirrhosis on a high sodium diet for five weeks. METHODS Sixteen biopsy proven preascitic cirrhotics were assessed at weekly intervals for five weeks on a diet of 200 mmol sodium...
متن کاملRenal distal tubular handling of sodium in central fluid volume homoeostasis in preascitic cirrhosis.
BACKGROUND/AIMS Patients with preascitic liver cirrhosis have an increased central plasma volume, and, for any given plasma aldosterone concentration, they excrete less sodium than healthy controls. A detailed study of the distribution of sodium reabsorption along the segments of the renal tubule, especially the distal one, is still lacking in preascitic cirrhosis. METHODS Twelve patients wit...
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Abnormal renal retention of sodium is a characteristic finding in both cirrhosis and fulminant hepatic failure. In cirrhosis the pathogenesis varies according to the level of renal perfusion. When this is normal, hyperaldosteronism is probably the most important factor and this results from an increased release of renin by the kidney. The stimulus to the latter may be a shunting of blood from t...
متن کاملSodium, kidney and renal sodium retention
The tight regulation of the body's sodium and chloride concentrations is so important that multiple mechanisms work in concert to control them, and a minimal amount of salt is required for survival. Sodium (Na) and chloride (Cl) are the principal ions in the extracellular fluid, especially in blood plasma. Sodium retention is the most common renal abnormality of cirrhosis and eventually leads t...
متن کاملClues to renal sodium retention.
EXPANSION OF EXTRACELLULAR VOLUME manifests as peripheral and pulmonary edema in chronic heart failure (CHF) patients and can lead to hospitalizations and death (1, 10). Stimulation of the autonomic nervous system, elevated levels of arginine vasopressin (AVP), and activation of the renin-angiotensinaldosterone systems are thought to contribute to the volume overload associated with this disord...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2002
ISSN: 0270-9139
DOI: 10.1053/jhep.2002.33714